allergyatlasCANADIAN TREATMENT GUIDEFor Canadian clinicians

SCIT builder.

01

Select allergens

Select clinically relevant allergens based on symptoms, exposure and sensitization.

Trees

Grass & weeds

Dust mites

Animals

Moulds Separate treatment sets

02

Mixing plan

Each treatment set contains one allergen mixture at four build-up concentrations. Each extract counts as one entry, including each mite species. Additional sets are used when compatibility or capacity requires.

Targets & supplier details

These are final maintenance-vial concentrations, not stock concentrates. The supplier prepares the mixture; this builder does not calculate stock volumes. Reference targets are not product verification.

PNU values require current supplier confirmation. Exact stock strengths, diluent, glycerin, compatibility and expiry remain with the preparing supplier.

Select allergens to see their targets and sources.

03

Build-up & maintenance

Aqueous SCIT · four concentrations · 0.50 mL maintenance target from the 1:1 vial.

BUILD-UP INTERVAL

32-injection schedule · clinician-selected
Vial 1 · 1:1,000

0.05 → 0.10 → 0.15 → 0.20 → 0.25 → 0.30 → 0.40 → 0.50 mL

Vial 2 · 1:100

0.05 → 0.10 → 0.15 → 0.20 → 0.25 → 0.30 → 0.40 → 0.50 mL

Vial 3 · 1:10

0.05 → 0.10 → 0.15 → 0.20 → 0.25 → 0.30 → 0.40 → 0.50 mL

Vial 4 · 1:1

0.05 → 0.10 → 0.15 → 0.20 → 0.25 → 0.30 → 0.40 → 0.50 mL

This clinician-selected template uses eight doses in each vial and differs from the CSACI appendix example. Weekly is the default; twice-weekly visits are at least 2 days apart. Dose progression, starting concentration and final maintenance dose need prescriber adjustment for sensitivity and reactions. This template is for aqueous environmental SCIT, not venom, rush or pre-seasonal depot products.

Compare the CSACI example ↗

Final formulation

Confirm compatibility, potency, stock volumes, diluent and the administration schedule with the allergist and preparing pharmacy. Clinical reference ↗

About Allergy Atlas

Payam Salimi

AUTHOR

Payam Salimi

PGY-4 · Clinical Immunology & Allergy
University of Manitoba

I created Allergy Atlas during my allergy residency as a practical educational resource. I’m continually updating the content, adding resources, and improving the site as I learn and receive feedback. I hope you find it useful.

If you notice an error, have a suggestion, or would like to get in touch, please contact salimip@myumanitoba.ca.

Reviewers & Advisors

Allergy Atlas continues to evolve with advice, feedback, and contributions from colleagues. Thank you to those helping improve this resource.

  • Dr. Lundy McKibbin (University of Manitoba)

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