allergyatlasCANADIAN TREATMENT GUIDEFor Canadian clinicians

Eczema topicals.

Treatment groups

Potency is specific to the ingredient, concentration and vehicle.

Vehicle
Corticosteroid contact allergyA · B · C · D1 · D2

Delayed contact allergy; separate from potency.

Select two entries to review their reported structural relationship.

Browse by structural class

Traditional overlaps

A with D2; budesonide (B) with D2. These patterns are incomplete.

Potency, vehicle, age and search filters still apply.

A guide, with limits

A different class does not establish tolerance. Patch testing should assess the suspected steroid, candidate alternatives and relevant vehicle ingredients.

In a Mayo Clinic series of 5,637 patients, patch-test copositivity did not reliably follow these groups. Copositivity does not prove cross-reactivity.

These groups do not predict immediate corticosteroid reactions.

24 treatment cards · 49 formulations

Corticosteroid

2–4 times daily · 2+ · clinician advice at age 2

Corticosteroid

2–3 times daily

Corticosteroid

0.05% creamSpectro EczemaCare

Twice daily · up to 7 days · 12+ · OTC

Corticosteroid

2–3 times daily

Corticosteroid

2–3 times daily

Corticosteroid

2–3 times daily · Adults

Corticosteroid
Historical US Dermatop.e · © 2005 GS

0.1% emollient creamDermatop

Twice daily · 1+ years

Corticosteroid

Once daily · 18+

Corticosteroid

Twice daily

Corticosteroid

2–4 times daily · Adults

Corticosteroid
Indian reference · Propynate NF

0.025% creamPropaderm

1–3 times daily

Corticosteroid
Representative · UK cream pack

Twice daily · 18+

Corticosteroid

2–3 times daily · Adults · child use not recommended

Corticosteroid
Historical US pack · © 2005 GS

Twice daily · 18+

Corticosteroid

0.01% topical oilDerma-Smoothe/FS

Adult: 2–3 times daily · Adults · children 3 months–12 years

Calcineurin inhibitor
International packaging

Tacrolimus

0.03% ointment

Apply a thin layer twice daily, morning and evening, for active disease

2+ years
Calcineurin inhibitor

Tacrolimus

0.1% ointment

Apply a thin layer twice daily, morning and evening, for active disease

16+ years
Calcineurin inhibitor

Pimecrolimus

1% cream

Apply a thin layer twice daily; stop when the skin clears

3+ months
PDE4 inhibitor

Crisaborole

2% ointment

Apply a thin layer to affected areas twice daily during active disease

3+ months
PDE4 inhibitor
US packaging

Roflumilast

0.15% cream

Apply once daily to affected areas and rub in completely

6+ years
PDE4 inhibitor
Representative · US 0.05% tube

Roflumilast

0.05% cream

Apply once daily to affected areas and rub in completely

2 to under 6 years
JAK inhibitor

Ruxolitinib

1.5% cream

Apply a thin layer twice daily, at least 8 hours apart, to no more than 20% body surface area

2+ years · AD
AhR agonist

Tapinarof

1% cream

Apply a thin layer once daily to clean, dry affected skin

2+ years · AD
JAK inhibitor
German pack · 60 g

Delgocitinib

2% cream · 20 mg/g

Apply a thin layer to affected hands and wrists twice daily, about 12 hours apart

18+ years

About Allergy Atlas

Payam Salimi

AUTHOR

Payam Salimi

PGY-4 · Clinical Immunology & Allergy
University of Manitoba

I created Allergy Atlas during my allergy residency as a practical educational resource. I’m continually updating the content, adding resources, and improving the site as I learn and receive feedback. I hope you find it useful.

If you notice an error, have a suggestion, or would like to get in touch, please contact salimip@myumanitoba.ca.

Reviewers & Advisors

Allergy Atlas continues to evolve with advice, feedback, and contributions from colleagues. Thank you to those helping improve this resource.

  • Dr. Lundy McKibbin (University of Manitoba)

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